Fluorescence microscopy to probe distributions, dynamics and interactions of cell components in cyanobacteria
My group works on the cell biology of cyanobacteria, and we have developed expertise in using fluorescence microscopy to visualise and quantify the sub-cellular distribution and dynamics of cell components including proteins, nucleic acids and fluorescent metabolite analogs. For this programme we are helping members of the SCyCode team to apply these approaches to understand the regulation of metabolism at the single-cell and sub-cellular scales in Synechocystis.
Fluorescence microscopy displays the localization of psaA mRNA (in green)
and thylakoid membranes (in red) in Synechocystis cells.
Prof. Conrad Mullineaux
Queen Mary University of London